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J Am Soc Nephrol (2003)

The second-generation tetracycline, minocycline, selectively inhibits the M1 state of microglial cells and exerts anti-neuroinflammatory effects in patients with AD (166)

In contrast to ketoacidosis, a pathologic state characterized by an anion gap metabolic acidosis with markedly elevated serum ketones, therapeutic ketosis aims for modest increases in -hydroxybutyrate without the corresponding acid-base and electrolyte disturbances observed in conditions such as diabetic ketoacidosis [111, 128]

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