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They were treated with antihistamines and steroids

For the experiment shown in Extended Data Fig
Muscle specimens from limb-specific Nf1Prx1 / conditional knockout mice show a 10-fold increase in muscle triglyceride content, upregulation in the activity of oxidative metabolism enzymes and increased expression of fatty acid synthase and of the hormone leptin, whereas the expression of a number of fatty acid transporters is decreased

Pandey MM, Rastogi S, Rawat AKS (2013) Indian traditional Ayurvedic system of medicine and nutritional supplementation

doi: 10.3390/dj7020048 69 AmmiratiAL

In this report, the production of antioxidants was negatively correlated with inactivation of FOXO3
