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Three times daily systemic (SC) treatment of DIO mice with 20 mg/kg of 5-amino-1MQ produced a progressive loss of body weight over the treatment period compared to controls (Figure 5A)

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Unlike saline-brain suspension inoculated mice (which did not differ from virus-suspension inoculated saline treated mice), no disease symptoms or death was observed in NaBPC157-brain suspension inoculated mice

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