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We expect that metabolic tracking of additional nutrients such as glutamine could be employed in NF1 patients for the unraveling of metabolically active lesions

StatPearls Publishing, Treasure Island (FL)

doi: 10.1155/2013/959261, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 33.Park HJ, Shim HS, Ahn YH, Kim KS, Park KJ, Choi WK, et al

vivax -infected reticulocytes to human spleen fibroblasts (hSFs) [3], suggesting a mechanism for parasite persistence in splenic tissue

Using luciferase reporter assays and DNA binding studies, they demonstrated that ATF4 directly binds to these elements, enhancing CHAC1 expression under ER stress conditions induced by chemicals like Thapsigargin and Tunicamycin

It reduces the production of lipid hydroperoxides in plasma [40]