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However, monotherapy with the Hh pathway inhibitor vismodegib did not show any significant antitumor activity in patients with ovarian cancer in a phase II clinical trial (NCT00739661) [189]

However, the sensitivity also depends on the nature of the viral envelope than on nucleic acid type [79]

doi: 10.1016/s0197-4580(97)00111-5 230

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CrossRef Cardiometabolic Therapies Shape Non-Coding RNA Landscapes in Cardiovascular Fibrosis Erica Floris, Francesco Nutile, Claudia Cozzolino, Virginia Pontecorvi, Antonella Bordin, Elena De Falco, Vittorio Picchio, Isotta Chimenti, Francesca Pagano Metabolites.2025