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Vitalriver Experimental Animal Technology Co., Ltd., Beijing, China) were used

compared the effects of 25 Hz and 100 Hz taVNS on PD gait and found that a stimulation frequency of 25 Hz was more effective in improving gait disorders, while a frequency of 100 Hz was more significant in increasing arm swing velocity (126)

At the same time, high-dose inhibition can be used for the removal of harmful substances both inside and outside organisms

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Acknowledgements This work was supported in part by Grants-in-Aid for Scientific Research (B) (grant numbers JP23K24259 and 23K22364 to MK, 21H03806 to TO) and a Grant-in-Aid for Young Scientists (grant number 21K15719 to YYA) from the Japan Society for the Promotion of Science

Further investigation verified that GPX4 is the target of RSL-3 through a binding site (Yang W