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Once Nrf2 translocates to the nucleus, it forms heterodimers with small Maf (MafG, MafK and MafF) and Jun (c-Jun, Jun-D, and Jun-B) proteins to bind to ARE [108]

SLC25A22 promotes proliferation and survival of colorectal cancer cells with kras mutations and xenograft tumor progression in mice via intracellular synthesis of aspartate

The Journal of Biochemistry

When ALD advances to cirrhosis, liver failure, or hepatocellular carcinoma, where the liver loses normal function and conventional treatments are ineffective, liver transplantation becomes the most effective method to increase survival rates by providing a normally functioning liver

doi: 10.1080/00365520310003471

Applying small molecules that activate autophagy to the back of mice can promote hair regeneration [9], but the mechanism by which autophagy promotes hair regeneration requires further investigation