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Feb 1 2018;144(2):115-126

Given the structural similarities among kavalactones, systematic investigations are needed to fully appreciate the potential of kavalactones in liver protection

Many studies show Jiaogulan can lower LDL which is the "bad" cholesterol and raise the HDL which is the "good" cholesterol thus generally regulating the body as an adaptogen

Therapeutic Modulation of GABAergic Signaling The therapeutic potential of modulating GABAergic transmission is significant, particularly in the treatment of seizure disorders, anxiety, and certain neurodegenerative diseases

The timing of symptoms can give clues

Compared to TNF-, the response of neural activity to IL-6 treatment is less clear in literature