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Important caveat: there are no completed human clinical trials of 5-Amino-1MQ

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( L ) Hierarchically clustered heatmap of the metabolic phenotypes of the clusters shown in J and K

In rodent and cell work, NNMT knockdown or inhibition has been described as protecting against diet-induced weight gain and improving metabolic measures without reducing food intake [5] [6]

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Molecular Genetics and Metabolism