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Abstract Melanotic neuroectodermal tumour of infancy (MNTI) is a locally aggressive neoplasm of neural crest origin

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However, while the AF3 prediction of NS3 binding to this region is compelling and supports the eCLIP data, previous studies showed no or only limited impact of mutations in SL3.1 and SL3.3, respectively, on RNA replication 69 , suggesting rather auxiliary than essential functions of this interaction

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TET2 negatively regulates nestin expression in human melanoma