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Ice application should be done as needed and can be combined with rest and NSAIDs for better results

Sleep-enhancing peptides exert systemic effects by acting on circadian regulators (e.g., CLOCK, BMAL1), restoring pineal-mitochondrial signaling, and enhancing endogenous GH release (Table 3)

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Sequence: Ac-Ser-Asp-Lys-Pro
