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The accumulation of A, as well as oxidative stress and other mechanisms of excitotoxicity, can lead to canonical activation of calpain through significant increases of Ca 2 + in the cytoplasm after NMDAR activation [59]

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For B12 deficiency, a typical injection dose is 1,000 mcg once a week for 4 to 8 weeks and then 1,000 mcg once a month

Yang ZC, Yi MJ, Ran N, Wang C, Fu P, Feng XY, Xu L, Qu ZH (2013) Transforming growth factor-beta1 induces bronchial epithelial cells to mesenchymal transition by activating the Snail pathway and promotes airway remodeling in asthma

In alveolar macrophages from patients with COPD, the use of siRNA to silence Nrf2 induction completely abolished the effect of sulforaphane upon recognition and the phagocytosis of clinical isolates of nontypeable Haemophilus influenza (NTHI) and Pseudomonas aeruginosa [65,66]