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Blood Samples Preparation The tube was inverted gently five times to mix the blood with the clot activator

[ref] CYP2E1 and oxidative pathway: The liver breaks down most of the acetaminophen using sulfation and glucuronidation reactions, allowing for easy excretion

Advantages in Preclinical Applications The enzymatic recycling assay offers several benefits for laboratory research

Pernelle JJ, Creuzet C, Loeb J, Gacon G

doi: 10.1016/j.schres.2014.06.027 66 NguyenTTKosciolekTEylerLTKnightRJesteDV

The method was adapted to allow for experimental measurements where the same readout was observed for multiple different test material treatments and concentrations, observed at different timepoints (Middleton et al., in preparation)
