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Biosynthetic pathways for histamine, gamma-aminobutyric acid (GABA), serotonin, and the catecholamines involve decarboxylation reactions that employ the coenzyme pyridoxal phosphate (PLP), a derivative of vitamin B6

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They observed that 7 patients who were passing fasciola eggs in their stools displayed distinct improvement of the general condition, drop in the egg count, and improvement of all signs and symptoms with no adverse side effects after treatment with the drug (Massoud et al., 2001)