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Description
Nicotinamide N-methyltransferase: a novel therapeutic target
AOD-9604 (Anti-Obesity Drug-9604) is a modified fragment of human growth hormone (hGH) that retains the fat-burning properties without the growth-promoting effects

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The deletion of PNPLA2 in adipocytes resulted in reduced PPAR activity and expression of target genes, including lower UCP1 protein levels and when exposed to cold, mice were cold sensitive (140)

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