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3) Promote blood vessel growth, increase skin oxygen supply, and activate skin

The problem is that MEM has shown no clear positive effects in clinical applications while, in preclinical stages, had very promising results

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Nichols et al., 2019

Measurement of reactive oxygen species, reactive nitrogen species, and Redox-Dependent signaling in the cardiovascular system: A scientific statement from the American heart association

Free iron that remains unsequestered or unexported can participate in the Fenton reaction, generating hydroxyl radicals and ultimately promoting increased reactive oxygen species (ROS) production and enhanced lipid peroxidation