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Analysis of endogenous substances and metabolites Endogenous substances in TCM include not only therapeutic constituents but also inherent toxic compounds, such as AC, pyrrolizidine alkaloids (PAs), aristolochic acid, and anthraquinones [54]

In addition, the relationship between sEV and hormones is far from entirely clear

After incubation in the dark at 4 C for 2 days, plates were cultivated in a growth chamber at 22 C with a 16 h/8 h light/dark (long day, LD) photoperiod

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