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10.1096/fj.06-7426com 16 ChenB

During their metabolic processes, gut microbiota generate numerous metabolites via fermentation, including short-chain fatty acids (SCFAs), tryptophan (Trp) and its indole derivatives, and bile acids [10]

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While histamine is involved with pro-inflammatory pathways, when subject to inflammatory conditions (such as treatment with LPS inflammogen), histamine inhibits chronic microglia activation and exhibits downregulatory effects [58]

Gardner, D

Patients with severe COVID-19 symptoms might need to stay in hospitals with intensive care units (ICU)