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Bottom Line Medical & Regulatory Disclaimer The information provided in this article is for educational purposes only and is not intended as medical advice

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Except for targeting mutant IDHs, metabolic inhibitors are potentially active regardless of tumor genetic subtype and thus beneficial to the large majority of men with CRPC who are not currently candidates for precision medicine (e.g., DNA repair defects for PARP inhibitors or CDK12 loss for immunotherapy) (138, 163)

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Disrupting the association of hepatitis C virus core protein with lipid droplets correlates with a loss in production of infectious virus

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doi: 10.1021/ac9014353

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