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This process reprograms the suppressive tumor microenvironment, characterized by increased DC maturation, elevated CD8 T-cell infiltration, and a reduction in regulatory T cells

Abstract The effectiveness of many anticancer drugs depends on the creation of specific metabolites that may alter their therapeutic or toxic properties

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Autophagy A mechanism through which unnecessary or damaged cellular components are degraded

Jisheng Liu, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers