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Common Symptoms of a Vitamin B12 Deficiency If you think you may be low, watch out for these symptoms: Feeling tired, fatigue and weakness Loss of appetite Constipation Weight loss Megaloblastic anemia Numbness and tingling Poor balance or coordination Confusion Memory loss Depression (21) Soreness of mouth and/or tongue (22) Be aware that many symptoms of B12 deficiency overlap with symptoms of other health conditions, so it's important to see your doctor for a definitive diagnosis

Later-phase trials remain stable , though Phase 2/3 studies are decreasingpotentially indicating a shift toward more discrete study phases

Over the next decade (1993-2002), Indomitable sailed two missions per year, primarily in the Caribbean Sea and Panama Canal

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Therefore, results obtained in isogenic models would highly benefit from validation in patient-derived primary cells and human samples in future studies

Crucial for Proper Functioning of your Brain and Nervous system - Vitamin B12 deficiency is particularly important for the brain and nervous system, because of its role in folate metabolism and DNA production