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More recently, a study by Francisco [286] showed that fermented rooibos consumption modulated postprandial glycaemia, lipaemia and oxidative stress in healthy subjects after an intake of a standardized fat meal

Pro-oxidants are reactive oxygen species that increase oxidative damage and inflammation

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The proportion of patients in whom ALT normalized was higher in the carnitine-orotate treatment group than in the control group (pooled odds ratio (OR), 95% confidence interval (CI) = 4.61 (1.4814.39))

The carnitines are essential in the metabolism of fatty acids and can act to protect from mitochondrial damage and altered energy balance conditions such as those present in polycystic ovary syndrome (PCOS) as also highlighted by the reduced levels of L-carnitine in the serum of patients with this disease

Additionally, to advance the understanding of ME/CFS pathophysiology, longitudinal studies should account for variables like physical activity and antibiotic use before disease onset