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ZT and AV screened CAIM entries in highly-accessed online encyclopaedias, HONcode searches, and a subset of the journal Aims and Scope webpages, both independently and in duplicate

Dundar HA, Kiray M, Kir M, Kolatan E, Bagriyanik A, Altun Z, et al

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3.3 Immune system enhancement The natural substances can act as immune checkpoint and co-inhibitory modulators, some polyphenols decrease the expression of tissue-and tumoural PD-L1 or of CTLA-4 on T cells giving a mechanistic reasoning to combination with nutritional support in patients treated with check point inhibitors, eventually reversing acquired resistance to treatment or decreasing the effective dose for drug administration (193)

When only samples that could be PCR-amplified with the assay procedure were taken into account, correct subtype determination was achieved in 99.6% and 99.2% of cases, respectively (Table 1)