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In GSTFs, the H-site involves residues located around the catalytic serine (N-terminal end of helix 1), in the loop 2-2 and in the C-terminal end of helix 4

The severity of lung injury was scored was evaluated based on the alveolar wall thickness, the amount of cellular infiltration and the level of hemorrhaging, as previously described with minor modifications (31)

Other reported neurobiological effects of ALCAR include modulation of: (1) brain energy and phospholipid metabolism