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Think of it like prepping the canvas before the artist starts painting

Neuroepidemiology 2012;38:117

Glia 32 , 247263 (2000)
The co-expression of ST and RAS V12 leads to the upregulation of topoisomerase I, thereby increasing cellular susceptibility to Erastin (Dolma et al., 2003)

A., and Ibrahim H

If you have active infections, inflammatory skin conditions, or open wounds, microneedling is not recommended until the skin heals