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Sci 312:436439 Necira K, Makki M, Sanz-Garca E, Canto T, Djilani-Khouadja F, Tenllado F (2021) Topical application of Escherichia coli -encapsulated dsRNA induces resistance in Nicotiana benthamiana to potato viruses and involves RDR6 and combined activities of DCL2 and DCL4