bpc-157 human clinical trials safety efficacy and the Difference Between an Evidence Gap and a Cover-Up: What the entire evidence base actually looks like, and the questions to ask next. — WellFounded The Hidden Risks of BPC‑157:
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[1] Removal of the colon by surgery may be necessary if the disease is severe, does not respond to treatment, or if complications such as colon cancer develop

Because BPC-157 lacks robust human safety data across the proposed routes of administration, the FDA states it does not have enough information to know whether compounded BPC-157 would cause harm in humans

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