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Some formulations of sodium chloride 0.9% may also contain preservatives for multi-dose use, while others are preservative-free single-use vials

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This has also occurred in humans, such as iatrogenic Creutzfeld-Jakob disease (Brown et al., 2012), variant CJD in the context of bovine spongiform encephalopathy (Diack et al., 2014), Lewy body pathology spreading to transplanted fetal neurons (Li et al., 2008) and possibly even Alzheimers or cerebral amyloid pathology from injection with contaminated human growth hormone extracts (Purro et al., 2018

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