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doi: 10.1016/j.addr.2013.09.019 406 BarenholzYC
Therefore, quantitative analysis of the GSH level is of great importance because of its biological significance and clinical relevance 9,10,11,12,13,14,15,16
This results in elevated lipid peroxidation and induction of ferroptosis (77)
Meanwhile, Akt activity is inhibited, accompanied by downstream activation of GSK3 and subsequent excessive phosphorylation of tau protein, forming a cascade of oxidative stress-IR-A/tau pathology, thereby accelerating AD progression [90, 91] (Fig
Madar Z, Hazan A
doi: 10.1016/j.clnu.2015.01.020
