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Description
A controversy circulated about the TMAO metabolite (associated with very high doses), but recent studies indicate that this effect is negligible at standard doses
Iwanaga, Z

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In a zebrafish model, compared with C3-carnitine, C18-carnitine and C18:1-carnitine can induce the inhibition of OXPHOS, interfere with the energy supply of cardiomyocytes, and lead to a significant impairment of cardiac systolic function, which manifests as a decreased heart rate and reduced shortening of the atrial and ventricular fractions [21]

Most of the reported cases occurred within the first year of drug use

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