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Studies have found that increased NRF2 signaling in the mouse liver is associated with repression of lipogenesis [75]

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For lupus, the evidence is largely preclinical and observational, but the mechanistic rationale is strong

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If a pregnant patient has a documented deficiency of one or more B vitamins or a condition like hyperemesis that prevents oral intake, the benefits of correcting the deficiency (preventing serious maternal and fetal complications) outweigh any minimal risk from the injection
