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Accordingly, we found that in vitro activation and the costimulatory potential of GSH-deficient FoB was decreased compared to control cells upon 24h stimulation as indicated by lower expression of CD25, CD69, GL-7 and CD80/CD86 (Supplementary Fig

After the completion of the study, it was noted that there appeared to be a significant reduction in the body weight of these murine models, including a reduction of excess body lipids

2.2 Lipid peroxidation and PUFA susceptibility Lipid peroxidation of polyunsaturated fatty acids (PUFAs), particularly within phospholipid membranes, is a defining feature of ferroptosis ( Key enzymes regulate the synthesis and incorporation of PUFAs into membrane phospholipids

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Serial dilutions of derivatized stock standard were added to the left wells