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This route of glutamine metabolism becomes the dominant source of cytosolic acetyl-CoA for lipogenesis under low-oxygen conditions

However, it is an invasive technique with possible complications, therefore non-invasive tests (NITs) have been identified (62)

doi: 10.1042/bj2920673

LH travels through the blood to the testes and signals Leydig cells to make testosterone [2]

1989;3:A1250

Saenz DT, Fiskus W, Manshouri T, Mill CP, Qian Y, Raina K, Rajapakshe K, Coarfa C, Soldi R, Bose P, Borthakur G , Kadia TM, Khoury JD, Masarova L, Nowak AJ, Sun B, Saenz DN, Kornblau SM, Horrigan S, Sharma S, Qiu P, Crews CM, Verstovsek S, Bhalla KN