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KD and KB are capable to increase mitochondrial respiration via an increase in ATP production and improve the efficiency of the mitochondrial respiratory chain complex with increased mitochondrial biogenesis (69)

Autophagy 12 , 225244

Retrieved October 28, 2025

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However, knockdown of Insig-2 in LIRKO mice only modestly increases nuclear SREBP-1c, suggesting that insulin regulates SREBP-1c processing through additional mechanisms other than Insig-2 transcriptional regulation (116)

Tempesta, L
