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The hypothalamic-pituitary-adrenal and the GH/IGF-I axis are also closely associated, as cortisol is required for physiological GH secretion
and p53 pathways governing cellular stress responses and DNA damage repair
doi:10.1158/1535-7163.MCT-12-0093 Liu L, Cao Y, Chen C et al (2006) Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5
On account of ROS being essential for existence and proliferation, cancer cells are invariably dependent on intracellular GSH
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Abnormal lipid metabolism with oxidative stress, ferroptosis and T cell dysfunction Previous studies on a small number of patients have reported conflicting results regarding the association between vitiligo and dyslipidemia
