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Likewise, this is the case for many other nutrients that support the closure of the neural tube, namely folate, choline, vitamin B6, zinc, and several more

Sterility Maintenance: Never use if packaging is damaged or open

In a cohort of pregnant women in Bangalore, India, with a high incidence of vitamin B-12 deficiency, we reported previously that women in the lowest tertile for plasma vitamin B-12 concentration during all 3 trimesters of pregnancy had significantly higher risk of IUGR that persisted after adjusting for maternal age, weight, education, and parity (12)

The complexity of B12 deficiency extends beyond simple dietary insufficiency

The injection site reactions deserve mention too

Individual tablets range in price from 85 to $4 for a 22.7 and 136 mg dosage, respectively