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The trial protocol was approved by the Madrid Region Clinical Research Ethics Committee ( Comit tico de Investigacin Clnica Regional de la Comunidad de Madrid ) on February 8 th 2011, and has been registered with ClinicalTrials.gov number NCT 01476007, and under EUDRACT number 2010-024129-20 [Oral Versus Intramuscular Cobalamin to treat Cobalamin Deficiency: Noninferiority randomised controlled trial, pragmatic and multi-center in the primary healthcare setting (OB12 project)]

Baillieres Clin Haematol 1995;8:679-97

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Useful as a single-source orientation paper before designing any new preclinical work in this space, and as the most up-to-date wound-healing-specific synthesis of the literature in a peer-reviewed journal