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TRIGR Study Group Hydrolyzed infant formula and early beta-cell autoimmunity: a randomized clinical trial JAMA 311 22: 2279-87

Cycle improvements are often seen within 13 months, but persistent anovulation should always be investigated medically

Amphetamine can also undergo aromatic hydroxylation to p -hydroxyamphetamine

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Precise identification of metabolic subphenotypes enables the selection of interventions that match individual pathophysiology, while chronotherapeutic strategies align treatment delivery with endogenous metabolic rhythms to maximize efficacy and minimize side effects (Table S7)