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Often related to infusion speed
Indeed, exploratory analysis of SZ and OD subgroups in the present study reveal mixed outcomes in relation to BOLD-fMRI, albeit impacting healthy control outcomes as well as patients, therefore more likely attributable to differing levels of variability between the subsamples, rather than a clear difference in function between the diagnostic groups in this instance

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Wang Y, Mo Y, Peng M, Zhang S, Gong Z, Yan Q, et al

Strategies such as HDAC inhibition, astrocyte transplantation and modulation of autophagy or metabolic pathways remain confined to experimental models, whereas GLP-1 receptor agonists and MAO-B inhibitors have advanced to clinical testing and show effects on astrocytic metabolism and neuroinflammation

IGF-1 has specific and stimulatory effects on granulosa cells, and it was reported to increase the expression of steroidogenic enzymes CYP11A1, 3-hroxysteroid dehydrogenase (3HSD), CYP19A1, along with IGF-1R, and FSHR gene expression (70)
