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Detoxification of potentially toxic metabolites A critical function of L-carnitine involves the detoxification of potentially toxic metabolites generated during intermediary metabolism, particularly those associated with impaired fatty acid -oxidation

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IDH1 inhibition decreased the HTML:TML ratio, l-carnitine:TML ratio and acetylcarnitine:TML ratio in this extract without altering acetyl-CoA (Extended Data Fig

doi:10.1016/j.jbior.2013.07.006

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