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McQueen, C

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Animal models attempting to replicate the dopaminergic pathology and clinical features of PD have been critical to our understanding of the pathogenic mechanisms of the disease

By consolidating mechanistic insight, clinical validation, safety profiling, pharmacokinetic challenges, and translational strategies into a unified model, this manuscript aims to provide an evidence-based and clinically actionable framework that extends beyond prior narrative summaries

The presented data were obtained from three independent experiments performed in duplicate