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Acetaminophen (APAP) toxicity, due to overdose, affects a large number of people in modern societies

Finally, the chemical structure of GSH provides peculiar characteristics ranging from un-susceptibility to proteolysis to redox thiols catalysis

EU air quality standards

showed that 13-oxo-ODE can activate PPAR, inducing transcriptional repression of pro-inflammatory factors and ameliorating colitis and mucosa inflammation in human epithelial colon cells, 170 whereas the two ALA-derived ketones, 9-oxo-OTrE and 13-oxo-OTrE inhibited inflammatory responses by significantly decreasing nitric oxide (NO) and TNF- release in a LPS-stimulated RAW 264.7 macrophage cell line

MPt: Writing original draft, Investigation, Conceptualization

Statistical analysis The statistical significance ( P 0.05) of treatments, cold storage durations and their interactions was assessed with two-way Analysis of Variance (ANOVA) and the Duncans Multiple Range Test by employing Genstat statistical system (24th edition, VSN International, Hemel Hempstead, UK)