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& Nourshargh, S
Al-Sumaih I, Johnston B, Donnelly M, ONeill C

The tryptophan catabolite picolinic acid selectively induces the chemokines macrophage inflammatory protein-1 alpha and -1 beta in macrophages
The body temperature of the mice was maintained at 37 C with circulating warm water
doi:10.1016/j.ijpharm.2020.119428 147

By downregulating NF-kB signaling, KPV reduces pro-inflammatory cytokine secretion without the immune suppression associated with corticosteroids or other pharmaceutical anti-inflammatories