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The mechanisms responsible for their effects involve the activation of distinct LOX protein subtypes, underscoring the diverse roles these enzymes play in driving ferroptotic cell death [23]

Glial contribution to excitatory and inhibitory synapse loss in neurodegeneration

Propionate exerts similar effects, whereas acetate demonstrates a dual role: in some contexts, it may stimulate the production of pro-inflammatory cytokines and enhance inflammation (Smolinska et al., 2017)

Median coverage was 106-fold

No published human clinical trials of Dihexa itself had reported as of 2026

Radiation-induced digestive injury is defined as acute or chronic lesions caused by ionizing radiation in the digestive organs, including the oral cavity, salivary glands, esophagus, stomach, intestines and anus