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Administration of high doses of biotin, and sometimes thiamine, has been shown to result in partial or complete improvement within days
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I.WuY.HuangR.SuD.WuY.LiuX.et al (2022)

Comorbidities were selected based on their known relevance for cognition in patients with dementia and included diabetes mellitus, arrythmia, heart failure, atrial fibrillation, alcohol-related disease, chronic kidney disease, cardiovascular disease, ischemic heart disease, respiratory disease, stroke, anaemia, liver disease, malignancy and obesity (Appendix)

Hall MJ, Levant S, DeFrances CJ

Additionally, glutathione reductase (GR) supports this antioxidant system by sustaining the glutathione (GSH) cycle and regeneration, thus enhancing the serums capacity for ROS detoxification 3
