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8+ Weeks: Long-Term Remodeling Few published BPC-157 studies extend beyond 8 weeks, but the available data and general tissue biology suggest: Tendon and ligament remodeling continues for 36 months post-injury regardless of intervention BPC-157's primary contribution (angiogenesis, growth factor upregulation) is most impactful in the first 48 weeks Continued dosing beyond 8 weeks is not well-studied

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[DOI] [PMC free article] [PubMed] [Google Scholar] Orecchioni M., Ghosheh Y., Pramod A.B., Ley K