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Coskun 2022 mmc3 Table 3 + mmc1 Table S8 Phase 1 single-ascending-dose study (NCT03841630, n=45, conducted in Singapore)

[DOI] [PubMed] [Google Scholar] 94.Van Zuiden M., Frijling J.L., Nawijn L., Koch S.B., Goslings J.C., Luitse J.S., Biesheuvel T.H., Honig A., Veltman D.J., Olff M

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This level is generally considered effective yet gentle enough to minimize the risk of irritation, especially for sensitive skin types

Users frequently report feeling younger and more vital after extended protocols, with improvements in energy, mobility, and resilience that suggest genuine tissue rejuvenation rather than simple symptom management