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The microneedling triggers the inflammatory phase of healing, releasing growth factors that signal fibroblasts to begin collagen production
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1Thymosin 4 and cardiac protection: implication in inflammation and fibrosisPubMed / Annals of the New York Academy of Sciences 2012 2Thymosin beta 4: a multi-functional regenerative peptidePubMed / Expert Opinion on Biological Therapy 2012
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Inactivation of PTEN activates Akt and -catenin [102]
