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2) NLRP3 inflammasome activation, triggered by Tat, gp120, and viral RNAs, which is exacerbated by ROS, ion flux changes, and impaired autophagy, with NF-B acting as a crucial priming signal for pyroptosis and pro-inflammatory cytokine release

Association between vitamin E and 28-Day mortality in adult sepsis patients: a retrospective cohort analysis

Motexafin-gadolinium and involved field radiation therapy for intrinsic pontine glioma of childhood: a children's oncology group phase 2 study

Antioxidants 11 , 1691 (2022)

Li S, Wang X, Xiao Y, Wang Y, Wan Y, Li X, Li Q, Tang X, Cai D, Ran B, Wu C (2021) Curcumin ameliorates mercuric chloride-induced liver injury via modulating cytochrome P450 signaling and Nrf2/HO-1 pathway

The oral bioavailability of GPS is relatively low (approximately 12%18%), primarily due to its poor water solubility caused by multiple polar hydroxyl groups in its molecular structure (Ren et al., 2023)