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Vellai, 2021), which in turn inhibits the retrograde response, the pathway which regulates the response to oxidative stress and which is the equivalent of the NF-B pathway in yeast ( Role of metal chelation in the regulation of CBS activity Several compounds identified in our drug screening point toward an important role of metal ion chelation in the regulation of CBS activity, as previously reported ( CBS overexpression in yeast and H 2 S production in HepG2 cells (Ostrakhovitch et al., 2002

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The copper complex should be protected from strong reducing agents (ascorbic acid, DTT) which can reduce Cu2+ to Cu+ and destabilize the complex

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Reduced expression of basal and probiotic-inducible G-CSF in intestinal mononuclear cells is associated with inflammatory bowel disease

10.1007/s12035-019-01742-2 77